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A Mesp1-dependent developmental breakpoint in transcriptional and epigenomic specification of early cardiac precursors

Transcriptional networks governing cardiac precursor cell (CPC) specification are incompletely understood owing, in part, to limitations in distinguishing CPCs from non-cardiac mesoderm in early gastrulation. We leveraged detection of early cardiac lineage transgenes within a granular single-cell tr...

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Detalles Bibliográficos
Autores principales: Krup, Alexis Leigh, Winchester, Sarah A. B., Ranade, Sanjeev S., Agrawal, Ayushi, Devine, W. Patrick, Sinha, Tanvi, Choudhary, Krishna, Dominguez, Martin H., Thomas, Reuben, Black, Brian L., Srivastava, Deepak, Bruneau, Benoit G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259516/
https://www.ncbi.nlm.nih.gov/pubmed/36994838
http://dx.doi.org/10.1242/dev.201229