Cargando…
A Mesp1-dependent developmental breakpoint in transcriptional and epigenomic specification of early cardiac precursors
Transcriptional networks governing cardiac precursor cell (CPC) specification are incompletely understood owing, in part, to limitations in distinguishing CPCs from non-cardiac mesoderm in early gastrulation. We leveraged detection of early cardiac lineage transgenes within a granular single-cell tr...
Autores principales: | Krup, Alexis Leigh, Winchester, Sarah A. B., Ranade, Sanjeev S., Agrawal, Ayushi, Devine, W. Patrick, Sinha, Tanvi, Choudhary, Krishna, Dominguez, Martin H., Thomas, Reuben, Black, Brian L., Srivastava, Deepak, Bruneau, Benoit G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259516/ https://www.ncbi.nlm.nih.gov/pubmed/36994838 http://dx.doi.org/10.1242/dev.201229 |
Ejemplares similares
-
Repurposing of the enhancer-promoter communication underlies the compensation of Mesp2 by Mesp1
por: Okada, Hajime, et al.
Publicado: (2022) -
How Mesp1 makes a move
por: Kelly, Robert G.
Publicado: (2016) -
Mesp1 controls the speed, polarity, and directionality of cardiovascular progenitor migration
por: Chiapparo, Giuseppe, et al.
Publicado: (2016) -
Aberrant expression of embryonic mesendoderm factor MESP1 promotes tumorigenesis
por: Tandon, Neha, et al.
Publicado: (2019) -
Uncovering the Number and Clonal Dynamics of Mesp1 Progenitors during Heart Morphogenesis
por: Chabab, Samira, et al.
Publicado: (2015)