Stretch regulates alveologenesis and homeostasis via mesenchymal G(αq/11)-mediated TGFβ2 activation

Alveolar development and repair require tight spatiotemporal regulation of numerous signalling pathways that are influenced by chemical and mechanical stimuli. Mesenchymal cells play key roles in numerous developmental processes. Transforming growth factor-β (TGFβ) is essential for alveologenesis an...

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Detalles Bibliográficos
Autores principales: Goodwin, Amanda T., John, Alison E., Joseph, Chitra, Habgood, Anthony, Tatler, Amanda L., Susztak, Katalin, Palmer, Matthew, Offermanns, Stefan, Henderson, Neil C., Jenkins, R. Gisli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259661/
https://www.ncbi.nlm.nih.gov/pubmed/37102682
http://dx.doi.org/10.1242/dev.201046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259661/
https://www.ncbi.nlm.nih.gov/pubmed/37102682
http://dx.doi.org/10.1242/dev.201046

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