Population pharmacokinetics of benznidazole in neonates, infants and children using a new pediatric formulation

BACKGROUND: There is a major need for information on pharmacokinetics (PK) of benznidazole (BNZ) in children with Chagas disease (CD). We conducted a multicentre population PK, safety and efficacy study in children, infants and neonates with CD treated with BNZ (formulated in 100 mg tablets or 12.5...

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Detalles Bibliográficos
Autores principales: Altcheh, Jaime, Moscatelli, Guillermo, Caruso, Martin, Moroni, Samanta, Bisio, Margarita, Miranda, Maria Rosa, Monla, Celia, Vaina, Maria, Valdez, Maria, Moran, Lucrecia, Ramirez, Teresa, Patiño, Oscar Ledesma, Riarte, Adelina, Gonzalez, Nicolas, Fernandes, Jayme, Alves, Fabiana, Ribeiro, Isabela, Garcia-Bournissen, Facundo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259795/
https://www.ncbi.nlm.nih.gov/pubmed/37256863
http://dx.doi.org/10.1371/journal.pntd.0010850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259795/
https://www.ncbi.nlm.nih.gov/pubmed/37256863
http://dx.doi.org/10.1371/journal.pntd.0010850

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