DIPG-32. PRECLINICAL TESTING OF THE EFFICACY AND SAFETY OF CRISPR/CAS9 GENE EDITED CAR-T CELL THERAPY FOR DIFFUSE MIDLINE GLIOMA (DMG)

DMGs are highly aggressive and difficult-to-treat brain tumors in children. Recent advances in Chimeric Antigen Receptor (CAR) expressing T cell therapy suggest application for brain tumors. Recent studies also demonstrate feasibility of GD2, Her2 and B7H3 CAR-T infusions in childhood brain tumors....

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Detalles Bibliográficos
Autores principales: Balakrishnan, Ilango, Leach, Lillie, Pierce, Angela, Lakshmanachetty, Senthilnath, Madhavan, Krishna, Fosmire, Susan, Chatwin, Hannah, Green, Adam, Fry, Terry, Vibhakar, Rajeev, Kohler, Eric M, Venkataraman, Sujatha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Diffuse Intrinsic Pontine Glioma/Diffuse Midline Gliomas - DPIG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259886/
http://dx.doi.org/10.1093/neuonc/noad073.079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259886/
http://dx.doi.org/10.1093/neuonc/noad073.079

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