DIPG-34. IMMUNE SYNAPSE OPTIMIZED GRP78-SPECIFIC CAR T CELLS ELICIT AN IMPROVED ANTITUMOR RESPONSE AGAINST DIPGS

Diffuse intrinsic pontine gliomas (DIPGs) are highly lethal pediatric brain tumors and a leading cause of cancer-related death in children. There is currently no cure for DIPG, highlighting an urgent need for novel therapeutics. Chimeric antigen receptor (CAR)-engineered T-cell therapy offers great...

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Detalles Bibliográficos
Autores principales: Ibanez, Jorge, Houke, Haley, Meehl, Michaela, Hebbar, Nikhil, Thanekar, Unmesha, Velasquez, Paulina, Krenciute, Giedre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Diffuse Intrinsic Pontine Glioma/Diffuse Midline Gliomas - DPIG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259894/
http://dx.doi.org/10.1093/neuonc/noad073.081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259894/
http://dx.doi.org/10.1093/neuonc/noad073.081

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