DIPG-41. EXPLORING BRAIN PENETRANT PEPTIDE-DRUG CONJUGATES IN DIFFUSE INTRINSIC PONTINE GLIOMA MODELS

The blood brain barrier (BBB) tightly controls access of molecules to the brain, limiting the efficacy of therapeutics for diseases of the central nervous system. We recently developed a novel approach for drug delivery across the BBB using a perfluoroaryl macrocyclic peptide-drug conjugate, M13-Pt(...

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Detalles Bibliográficos
Autores principales: Clark, Jasmine, McKinnon, Samuel, JImenez-Macias, Jorge_Luis, Miller, Edward, Loas, Andrei, Pentelute, Brad, Lulla, Rishi, Lawler, Sean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Diffuse Intrinsic Pontine Glioma/Diffuse Midline Gliomas - DPIG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259897/
http://dx.doi.org/10.1093/neuonc/noad073.088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259897/
http://dx.doi.org/10.1093/neuonc/noad073.088

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