ATRT-17. CAR T CELL THERAPY TARGETING CLAUDIN-6 IS EFFECTIVE IN CELLULAR AND XENOGRAFT MODELS OF ATYPICAL TERATOID/RHABDOID TUMOR

Novel therapies are needed to for the treatment of atypical teratoid/rhabdoid tumor (ATRT), an aggressive brain tumor that predominantly affects young children and has an average 5-year survival under 50%. Claudin-6 (CLDN6) is a tight junction protein present during development and is expressed in u...

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Detalles Bibliográficos
Autores principales: Madsen, Peter, Stern, Allison, Dickson, Conor, Wilson, Cullen, Patterson, Luke, Harvey, Kyra, Griffin, Crystal, Oehm, Petra, Rengstl, Benjamin, Flemmig, Carina, Storm, Phillip, Resnick, Adam, Foster, Jessica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: ATRT/Embryonal/ETMR - ATRT
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259899/
http://dx.doi.org/10.1093/neuonc/noad073.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259899/
http://dx.doi.org/10.1093/neuonc/noad073.017

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