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ATRT-17. CAR T CELL THERAPY TARGETING CLAUDIN-6 IS EFFECTIVE IN CELLULAR AND XENOGRAFT MODELS OF ATYPICAL TERATOID/RHABDOID TUMOR
Novel therapies are needed to for the treatment of atypical teratoid/rhabdoid tumor (ATRT), an aggressive brain tumor that predominantly affects young children and has an average 5-year survival under 50%. Claudin-6 (CLDN6) is a tight junction protein present during development and is expressed in u...
Autores principales: | Madsen, Peter, Stern, Allison, Dickson, Conor, Wilson, Cullen, Patterson, Luke, Harvey, Kyra, Griffin, Crystal, Oehm, Petra, Rengstl, Benjamin, Flemmig, Carina, Storm, Phillip, Resnick, Adam, Foster, Jessica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259899/ http://dx.doi.org/10.1093/neuonc/noad073.017 |
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