DIPG-09. ATOVAQUONE RADIOSENSITISES DIFFUSE MIDLINE GLIOMAS BY INHIBITING MITOCHONDRIAL METABOLISM AND HYPOXIA

Diffuse Midline Glioma (DMG) is a uniformly fatal paediatric brainstem tumour with median survival of less than 1 year. Radiotherapy has been the only effective treatment for decades, but most DMGs recur within several months due to radioresistance. The hypoxic tumour microenvironment, a main featur...

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Detalles Bibliográficos
Autores principales: Mudassar, Faiqa, Chang, Cecilia, Ing, Prunella, Nguyen, Sandy, Cook, Kristina M, Warnken, Zachary N, O’Neill, Geraldine, Shen, Han, Hau, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Diffuse Intrinsic Pontine Glioma/Diffuse Midline Gliomas - DPIG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259914/
http://dx.doi.org/10.1093/neuonc/noad073.056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259914/
http://dx.doi.org/10.1093/neuonc/noad073.056

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