LGG-04. CLINICALLY RELEVANT MODELING OF FUSION-DRIVEN PEDIATRIC LOW GRADE GLIOMAS USING DROSOPHILA MELANOGASTER

Pediatric low-grade gliomas (PLGGs) are the most common brain tumors in children, with varying degrees of brain invasion. Recent whole-genome sequencing has identified a rare gene fusion involving RAF1, a RAF isoform. Unlike other RAF fusions, RAF1 fusions are resistant to existing RAF inhibitors. T...

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Detalles Bibliográficos
Autores principales: Jung, Geena, Jain, Payal, Liang, Zizhuo, Li, Feng, Rathi, Komal, Chen, Xin, Straka, Joshua, Koptyra, Mateusz, Sanchez-maldonado, Stephanie, Fathikazerooni, Anahita, Familiar, Ariana, Nabavizadeh, Ali, Waanders, Angela, Huang, Xi, Resnick, Adam, Song, Yuanquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Low Grade Gliomas - LGG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259918/
http://dx.doi.org/10.1093/neuonc/noad073.214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259918/
http://dx.doi.org/10.1093/neuonc/noad073.214

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