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SURG-06. ENHANCED DELIVERY OF ANTI-PD1 FOR TREATMENT OF DIFFUSE MIDLINE GLIOMA USING FOCUSED ULTRASOUND-MEDIATED BLOOD-BRAIN BARRIER OPENING

Diffuse midline glioma with H3K27 mutation is a fatal central nervous system tumor, most commonly arising in the brainstem. Despite a multitude of clinical trials, prognosis remains poor with a median overall survival of 9-12 months. Immune-checkpoint inhibitors (ICIs) have transformed the treatment...

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Detalles Bibliográficos
Autores principales: Kokossis, Danae, Wei, Hong-Jian, Gallitto, Matthew, Yoh, Nina, McQuillan, Nicholas, Tazhibi, Masih, Berg, Xander, Zhang, Xu, Szalontay, Luca, Gartrell, Robyn D, Pavisic, Jovana, Zhang, Zhiguo, Molotkov, Andrei, Mintz, Akiva, Konofagou, Elisa E, Wu, Cheng-Chia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259928/
http://dx.doi.org/10.1093/neuonc/noad073.282