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MDB-04. SINGLE-CELL TRANSCRIPTOMIC ANALYSIS REVEALS DISTINCT GENOMIC LANDSCAPES, CELL TRAJECTORIES, AND TUMOUR-MICROENVIRONMENT INTERACTIONS IN FOUR SUBTYPES OF MEDULLOBLASTOMA

Medulloblastoma is the most common paediatric high-grade brain tumour, which comprises four different molecular subtypes (SHH, Wnt, Group 3, and Group 4), each defined by different molecular characteristics, genomic aberrations, and prognosis. High levels of inter- and intra-tumoural heterogeneity,...

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Detalles Bibliográficos
Autores principales: Ruchiy, Yana, Tsea, Ioanna, Verhoeven, Bronte Manouk, Sinha, Indranil, Preka, Efthalia, Olsen, Thale Kristin, Mei, Shenglin, Blomgren, Klas, Johnsen, John Inge, Carlson, Lena-Maria, Dyberg, Cecilia, Baryawno, Ninib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259932/
http://dx.doi.org/10.1093/neuonc/noad073.237