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MDB-04. SINGLE-CELL TRANSCRIPTOMIC ANALYSIS REVEALS DISTINCT GENOMIC LANDSCAPES, CELL TRAJECTORIES, AND TUMOUR-MICROENVIRONMENT INTERACTIONS IN FOUR SUBTYPES OF MEDULLOBLASTOMA
Medulloblastoma is the most common paediatric high-grade brain tumour, which comprises four different molecular subtypes (SHH, Wnt, Group 3, and Group 4), each defined by different molecular characteristics, genomic aberrations, and prognosis. High levels of inter- and intra-tumoural heterogeneity,...
Autores principales: | Ruchiy, Yana, Tsea, Ioanna, Verhoeven, Bronte Manouk, Sinha, Indranil, Preka, Efthalia, Olsen, Thale Kristin, Mei, Shenglin, Blomgren, Klas, Johnsen, John Inge, Carlson, Lena-Maria, Dyberg, Cecilia, Baryawno, Ninib |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259932/ http://dx.doi.org/10.1093/neuonc/noad073.237 |
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