BIOL-13. DEPLOYING NEW MODELS OF NF-1 MUTANT LOW GRADE GLIOMA TO ACCELERATE THERAPEUTIC DEVELOPMENT

Pediatric low grade glioma (pLGG) research is hampered by a paucity of genetically accurate cell line models and xenografts. To address this need, we have developed and characterized multiple in vivo and organoid models. We used cell reprogramming conditions (CRC) to establish and propagate JHH-NF1-...

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Detalles Bibliográficos
Autores principales: Alaali, Lujain, Xu, Jinchong, Mumm, Jeff, Yuan, Ming, Eberhart, Charles, Raabe, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Basic Biology/Stem Cells/Models - BIOL
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259946/
http://dx.doi.org/10.1093/neuonc/noad073.032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259946/
http://dx.doi.org/10.1093/neuonc/noad073.032

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