LGG-14. TREATMENT OF TWO PEDIATRIC FGFR-ALTERED LOW-GRADE GLIONEURONAL TUMORS WITH MEK INHIBITION

Somatic alterations in the fibroblast growth factor receptor (FGFR) gene family (FGFR1/2/3) have been implicated in tumorigenesis across pediatric low-grade glioneuronal neoplasms and represent a potential therapeutic target. FGFR rearrangements and internal tandem duplication (ITD) cause constituti...

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Detalles Bibliográficos
Autores principales: Lazow, Margot, Thomas, Diana, Cottrell, Catherine, Kobolt, Daniel, Ramadesikan, Swetha, Salloum, Ralph, Shaikhouni, Ammar, Mardis, Elaine, Jones, Jeremy, Leonard, Jeffrey, Boué, Daniel, Fouladi, Maryam, Schieffer, Kathleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Low Grade Gliomas - LGG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259957/
http://dx.doi.org/10.1093/neuonc/noad073.224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259957/
http://dx.doi.org/10.1093/neuonc/noad073.224

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