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MDB-32. TRANSLATION OF NON-CANONICAL OPEN READING FRAMES AS A CANCER CELL SURVIVAL MECHANISM IN CHILDHOOD MEDULLOBLASTOMA

High-risk medulloblastoma is one of the most recalcitrant pediatric cancers, and children with MYC-amplified disease frequently succumb to relapsed disease. Extensive analyses of the coding genome in this disease have characterized additional somatic events in some subsets of patients, though most t...

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Detalles Bibliográficos
Autores principales: Hofman, Damon, Ruiz-Orera, Jorge, Yannuzzi, Ian, Murugesan, Rakesh, van Dinter, Jip, Clauser, Karl, Condurat, Alexandra, Herman, Amy, Shanmugam, Vignesh, Zhou, Kevin, Vogelzang, Jayne, Wang, Li, Roth, Jennifer, Ligon, Keith, Phoenix, Timothy, Root, David, Golub, Todd, Bandopadhayay, Pratiti, van Heesch, Sebastiaan, Prensner, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259982/
http://dx.doi.org/10.1093/neuonc/noad073.264