HGG-23. DECIPHERING THE RELATIONSHIP OF MICROSATELLITE-INSTABILITY AND MUTATIONAL BURDEN IN HIGH-GRADE GLIOMA PATIENTS WITH CONSTITUTIONALLY IMPAIRED DNA DAMAGE RESPONSE

Multiple large-scale genomic studies across pediatric tumors have reported an overall frequency of ~6-10% of patients with constitutional pathogenic variants, but associations of cancer predisposition with distinct tumor types vary between zero and 100%. We analyzed sequencing and DNA methylation da...

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Detalles Bibliográficos
Autores principales: Blattner-Johnson, Mirjam, Sturm, Dominik, Jones, Barbara C, Previti, Christopher, Sievers, Philipp, Jäger, Natalie, Hirsch, Steffen, Dikow, Nicola, Sahm, Felix, Kramm, Christof M, Witt, Olaf, Pfister, Stefan M, Jones, David T W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: High Grade Glioma/Gliomatosis Cerebri - HGG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259991/
http://dx.doi.org/10.1093/neuonc/noad073.172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10259991/
http://dx.doi.org/10.1093/neuonc/noad073.172

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