DIPG-40. HYPOXIC STRESS EXPOSES EPIGENETIC TARGETS TO ENHANCE RADIOTHERAPY RESPONSE IN H3K27M-POSITIVE PEDIATRIC DIFFUSE MIDLINE GLIOMAS

Diffuse midline gliomas (DMGs) are the most challenging to treat pediatric high-grade gliomas, with a dismal prognosis of 9 to 15 months of median survival. The ones localized in the pons are not accessible to the surgery and rely on radiotherapy treatment. The majority of DMGs confer a mutation in...

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Detalles Bibliográficos
Autores principales: de Freitas, Amanda Pereira, Dzwigonska, Monika, Trubicka, Joanna, Grajkowska, Wieslawa, Mieczkowski, Jakub, Kaminska, Bozena, Leszczynska, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Diffuse Intrinsic Pontine Glioma/Diffuse Midline Gliomas - DPIG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260003/
http://dx.doi.org/10.1093/neuonc/noad073.087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260003/
http://dx.doi.org/10.1093/neuonc/noad073.087

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