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DIPG-26. CLINICAL AND GENOMIC ANALYSIS OF H3K27M-DMG LONG-TERM SURVIVORS REVEALS ENRICHMENT IN MAPK PATHWAY ALTERATIONS

INTRODUCTION: H3K27M-mutant diffuse midline gliomas (H3K27M-DMGs) share a generally poor prognosis with a median overall survival (OS) of 9–12 months. However, patients with histone-mutant central nervous system (CNS) tumors and long-term survival (LTS) have been reported, in some instances beyond t...

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Detalles Bibliográficos
Autores principales: Roberts, Holly, Picca, Alberto, Sanson, Marc, Schüller, Ulrich, Picart, Thiébaud, Ducray, François, Green, Adam, Nakano, Yoshiko, Sturm, Dominik, Abdullaev, Zied, Aldape, Kenneth, Waszak, Sebastian, Venneti, Sriram, Pratt, Drew, Koschmann, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260005/
http://dx.doi.org/10.1093/neuonc/noad073.073