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MDB-09. IMPACT OF PRDM6 ON CHROMATIN ACCESSIBILITY, GENE EXPRESSION, AND MEDULLOBLASTOMA FORMATION

Group 4 medulloblastoma (MB) is the most common medulloblastoma subgroup and shows high incidence of metastasis and late-onset relapse cases. These tumors lack a unifying oncogenic driver and treatment targets, despite extensive genomic characterization. Group 4 MBs are characterized by recurrent ge...

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Detalles Bibliográficos
Autores principales: Schmidt, Christin, Husain, Sarah, Carlson, Annika, Cohen, Sarah, Westelman, Samantha, Wang, Linyu, Weiss, William, Schwer, Bjoern
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260009/
http://dx.doi.org/10.1093/neuonc/noad073.242