Cargando…

Pancreatic tumors exhibit myeloid-driven amino acid stress and upregulate arginine biosynthesis

Nutrient stress in the tumor microenvironment requires cancer cells to adopt adaptive metabolic programs for survival and proliferation. Therefore, knowledge of microenvironmental nutrient levels and how cancer cells cope with such nutrition is critical to understand the metabolism underpinning canc...

Descripción completa

Detalles Bibliográficos
Autores principales: Apiz Saab, Juan J, Dzierozynski, Lindsey N, Jonker, Patrick B, AminiTabrizi, Roya, Shah, Hardik, Menjivar, Rosa Elena, Scott, Andrew J, Nwosu, Zeribe C, Zhu, Zhou, Chen, Riona N, Oh, Moses, Sheehan, Colin, Wahl, Daniel R, Pasca di Magliano, Marina, Lyssiotis, Costas A, Macleod, Kay F, Weber, Christopher R, Muir, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260022/
https://www.ncbi.nlm.nih.gov/pubmed/37254839
http://dx.doi.org/10.7554/eLife.81289