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Pancreatic tumors exhibit myeloid-driven amino acid stress and upregulate arginine biosynthesis
Nutrient stress in the tumor microenvironment requires cancer cells to adopt adaptive metabolic programs for survival and proliferation. Therefore, knowledge of microenvironmental nutrient levels and how cancer cells cope with such nutrition is critical to understand the metabolism underpinning canc...
Autores principales: | Apiz Saab, Juan J, Dzierozynski, Lindsey N, Jonker, Patrick B, AminiTabrizi, Roya, Shah, Hardik, Menjivar, Rosa Elena, Scott, Andrew J, Nwosu, Zeribe C, Zhu, Zhou, Chen, Riona N, Oh, Moses, Sheehan, Colin, Wahl, Daniel R, Pasca di Magliano, Marina, Lyssiotis, Costas A, Macleod, Kay F, Weber, Christopher R, Muir, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260022/ https://www.ncbi.nlm.nih.gov/pubmed/37254839 http://dx.doi.org/10.7554/eLife.81289 |
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