DIPG-21. LINKING DETERMINATION OF CELL FATE IN THE DEVELOPING CENTRAL NERVOUS SYSTEM TO DIFFUSE MIDLINE GLIOMA

Diffuse midline glioma, K27-altered (DMG) is a treatment resistant, uniformly fatal cancer that arises predominantly in children. Next-generation sequencing has revealed that the majority of patients with DMG harbor K27M mutations in canonical histone variants H3.1 and H3.3, leading to global epigen...

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Detalles Bibliográficos
Autores principales: Furst, Liam, Roussel, Enola, Leung, Ryan, George, Ankita, Firestein, Ron, Faux, Maree, Eisenstat, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Diffuse Intrinsic Pontine Glioma/Diffuse Midline Gliomas - DPIG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260029/
http://dx.doi.org/10.1093/neuonc/noad073.068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260029/
http://dx.doi.org/10.1093/neuonc/noad073.068

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