IMMU-10. PILOCYTIC ASTROCYTOMAS SHOW EVIDENCE OF INTRINSIC IMMUNE SURVEILLANCE AND ACTIVATION WITHIN THE TUMOR MICROENVIRONMENT

PURPOSE: To clarify the immunoreactivity and potential immunotherapeutic targets of pediatric low- and high-grade gliomas (HGG). METHODS: Spatial sequential immunofluorescence (seqIFTM) of 24 protein markers, NanoString analysis of 770 immune genes, and scRNA sequencing were used to profile and char...

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Detalles Bibliográficos
Autores principales: Najem, Hinda, Tripathi, Shashwat, McCortney, Kathleen, Horak, Victoria Jane, Leonard, Kaethe, Steffens, Alicia, Walshon, Jordain, Horbinski, Craig M, Wadhwani, Nitin R, James, Charles David, Lam, Sandi, Lesniak, Maciej S, Burks, Jared K, Heimberger, Amy B, DeCuypere, Michael G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Immunology/Immunotherapy - IMMU
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260064/
http://dx.doi.org/10.1093/neuonc/noad073.197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260064/
http://dx.doi.org/10.1093/neuonc/noad073.197

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