ATRT-08. THE SINGLE-CELL LANDSCAPE OF PINEOBLASTOMA IDENTIFIES DEVELOPMENTAL ORIGINS AND EXPOSES TUMORIGENIC DEPENDENCIES

Pineoblastoma (PB), a rare and aggressive brain tumor affecting children, presents with a highly variable age distribution and treatment outcome. Our recent bulk tumor analyses of DNA methylation and mutational landscapes uncovered four discrete PB molecular subgroups (PB-miRNA1, PB-miRNA2, PB-MYC/F...

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Detalles Bibliográficos
Autores principales: Gudenas, Brian, Englinger, Bernhard, Liu, Anthony P Y, Ahmad, Sheikh Tanveer, Meredith, David, Pfaff, Elke, Paul, Leena, Hadley, Jennifer, Batts, Melissa, Klimo Jr., Paul, Boop, Frederick A, Gajjar, Amar, Robinson, Giles W, Orr, Brent A, Lin, Hong, Alexandrescu, Sanda, Jones, David T W, Filbin, Mariella G, Northcott, Paul A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: ATRT/Embryonal/ETMR - ATRT
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260074/
http://dx.doi.org/10.1093/neuonc/noad073.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260074/
http://dx.doi.org/10.1093/neuonc/noad073.008

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