DIPG-33. P16 IMMUNOHISTOCHEMICAL EXPRESSION AS A SURROGATE ASSESSMENT OF CDKN2A ALTERATION IN GLIOMAS LEADING TO PROGNOSTIC SIGNIFICANCES

CDKN2A is a tumor suppressor gene encoding for p16 protein. Its homozygous deletion is a central prognostic factor for numerous brain cancers. This deletion can be detected by several techniques. Up to now, immunohistochemistry (IHC) using p16 antibody is not recommended as a surrogate test. This st...

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Detalles Bibliográficos
Autores principales: Geyer, Lucas, Wolf, Thibaut, Chenard, Marie Pierre, Cebula, Helene, Schott, Roland, Noel, Georges, Guerin, Eric, Pencreach, Erwan, Reita, Damien, ENTZ-WERLE, Natacha, Lhermitte, Benoit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Diffuse Intrinsic Pontine Glioma/Diffuse Midline Gliomas - DPIG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260083/
http://dx.doi.org/10.1093/neuonc/noad073.080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260083/
http://dx.doi.org/10.1093/neuonc/noad073.080

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