LGG-23. OUTCOMES UTILIZING BRAF INHIBITION MONOTHERAPY IN BRAF(V600E) MUTATED PEDIATRIC LOW GRADE GLIOMAS

BACKGROUND: Pediatric low-grade glioma (pLGG) tumorigenesis is driven by activation of the RAS/RAF/MAPK pathway. pLGGs have an overall survival over 95%; however, patients harboring a BRAF(V600E) alteration may have worse outcomes. Combined BRAF/MEK inhibition following incomplete resection demonstr...

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Detalles Bibliográficos
Autores principales: McThenia, Sheila, Reddy, Kartik, Goldman-Yassen, Adam E, Gray, Rachel, Connelly, Erin, Patteson, Brooke, Aguilera, Dolly, Castellino, Robert Craig, Fangusaro, Jason Ronald, Janss, Anna, Mazewski, Claire, MacDonald, Tobey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Low Grade Gliomas - LGG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260090/
http://dx.doi.org/10.1093/neuonc/noad073.232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260090/
http://dx.doi.org/10.1093/neuonc/noad073.232

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