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MDB-17. THE PTBP2 SPLICING FACTOR IS ESSENTIAL IN GROUP 3/4 MEDULLOBLASTOMA

Medulloblastoma (MB) is a common malignant pediatric brain tumor with significant heterogeneity among its four molecular subgroups WNT, SHH, Group 3 and 4. Group 3/4 MB are aggressive with a relatively poor prognosis indicating a critical need for novel therapeutic targets. Since the transcriptomic...

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Detalles Bibliográficos
Autores principales: Caisova, Veronika, Rivero-Hinojosa, Samuel, Chintala, Navya, Lu, I-An, Huizhen, Zhang, Mochizuki, Aaron, Yang, Jianhua, Rood, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260109/
http://dx.doi.org/10.1093/neuonc/noad073.250