DIPG-17. TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA USING ALLELE-SPECIFIC SIRNA TARGETING H3.3 K27M MUTANT HISTONE

In recent years CNS tumors have surpassed leukemia and lymphoma as the deadliest forms of pediatric cancer, yet many of these tumors remain resistant to treatment. Understanding of the molecular pathology of a particularly fatal pediatric glioma, diffuse intrinsic pontine glioma (DIPG), has improved...

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Detalles Bibliográficos
Autores principales: Wentworth, Simon, Batista, Ana Rita, Alterman, Julia, Khvorova, Anastasia, Sena-Esteves, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Diffuse Intrinsic Pontine Glioma/Diffuse Midline Gliomas - DPIG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260116/
http://dx.doi.org/10.1093/neuonc/noad073.064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260116/
http://dx.doi.org/10.1093/neuonc/noad073.064

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