TRLS-02. FEASIBILITY OF EVALUATING ABEMACICLIB NEUROPHARMACOKINETICS OF DIFFUSE MIDLINE GLIOMA USING INTRATUMORAL MICRODIALYSIS

BACKGROUND: Diffuse midline gliomas (DMG) are the most aggressive brain tumors of childhood and young adults, with documented 2-year survival rates <10%. Treatment failure is due in part to the function of the BBB. Intratumoral microdialysis sampling is an effective tool to determine brain entry...

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Detalles Bibliográficos
Autores principales: Jackson, Sadhana, Glod, John, Peer, Cody, Figg, William, Dalmage, Mahalia, Brown, Desmond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Translational Therapeutics/Clinical Trials - TRLS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260119/
http://dx.doi.org/10.1093/neuonc/noad073.305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260119/
http://dx.doi.org/10.1093/neuonc/noad073.305

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