IMMU-13. PRECLINICAL EFFICACY OF MULTI-ANTIGEN (HER2/EGFR806/B7-H3/IL13RA2) TARGETING QUAD-CAR T CELLS AGAINST DIFFUSE MIDLINE GLIOMA

BACKGROUND: Diffuse midline glioma (DMG), including diffuse intrinsic pontine glioma (DIPG), remains a fatal disease. We have published the preclinical efficacy of HER2, EGFR806, and B7-H3 CAR-T cells and opened 3 trials (BrainChild-01, -02, and -03, respectively) that have delivered >350 intracr...

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Detalles Bibliográficos
Autores principales: Myers, Carrie, Timpanaro, Andrea, Song, Edward, Meechan, Michael, Chen, Alex, Biery, Matthew, Reid, Aquene, Gwiazda, Kamila, Baldwin, Michael, Gustafson, Joshua, Gardner, Rebecca, Jensen, Michael, Vitanza, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Immunology/Immunotherapy - IMMU
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260133/
http://dx.doi.org/10.1093/neuonc/noad073.200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260133/
http://dx.doi.org/10.1093/neuonc/noad073.200

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