BIOL-07. DISTINCTIVE FEATURES OF HIGH-GRADE GLIOMA MOUSE MODELS REVEALED BY SINGLE-NUCLEUS RNA-SEQUENCING GUIDE PRE-CLINICAL MODEL SELECTION

Glioma is the most common pediatric central nervous system tumor, with high-grade gliomas (HGG) having one of the worst prognoses of all human cancers. In order to develop better diagnostics and therapies, it is essential to use faithful disease models. Currently, highly passaged patient-derived xen...

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Detalles Bibliográficos
Autores principales: Ernst, Kati, Okonechnikov, Konstantin, von Soosten, Laura, Hofmann, Nina, Mack, Norman, Schwalm, Benjamin, Wechsler-Reya, Robert J, Pfister, Stefan M, Thongjuea, Supat, Jones, David T W, Zuckermann, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Basic Biology/Stem Cells/Models - BIOL
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260139/
http://dx.doi.org/10.1093/neuonc/noad073.026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260139/
http://dx.doi.org/10.1093/neuonc/noad073.026

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