DIPG-16. ACUTE VERSUS PROLONGED CONVECTION-ENHANCED DELIVERY OF ALISERTIB INTO H3 K27M-MUTANT MODELS OF DIFFUSE MIDLINE GLIOMA

Convection-enhanced delivery (CED) is a potentially promising strategy to administer therapeutics directly into the brainstem of children harboring H3 K27-altered diffuse midline glioma (DMG). While early-phase clinical trials have demonstrated the safety of this technique, efficacy has yet to be ac...

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Detalles Bibliográficos
Autores principales: Rechberger, Julian S, Zhang, Liang, Ge, Jizhi, Daniels, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Diffuse Intrinsic Pontine Glioma/Diffuse Midline Gliomas - DPIG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260146/
http://dx.doi.org/10.1093/neuonc/noad073.063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260146/
http://dx.doi.org/10.1093/neuonc/noad073.063

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