TRLS-10. ROVER: A PHASE 1/2 STUDY OF AVAPRITINIB IN PEDIATRIC PATIENTS WITH SOLID TUMORS DEPENDENT ON KIT OR PDGFRA SIGNALING

Pediatric patients with advanced relapsed/refractory (R/R) solid (including central nervous system [CNS]) tumors have poor prognoses. KIT alterations are common in germ cell tumors and high-grade glioma (HGG); platelet-derived growth factor receptor alpha (PDGFRA) alterations are common in sarcoma a...

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Detalles Bibliográficos
Autores principales: Koschmann, Carl, Hoffman, Lindsey M, Kramm, Christof M, Plant-Fox, Ashley, Abdelbaki, Mohamed S, Bui, Ashley, Casanova, Michela, Morgenstern, Daniel A, Swamy, Preethi, Shi, Hongliang, Hong, Janet, Rinne, Mikael L, Chi, Susan N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Translational Therapeutics/Clinical Trials - TRLS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260153/
http://dx.doi.org/10.1093/neuonc/noad073.313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260153/
http://dx.doi.org/10.1093/neuonc/noad073.313

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