HGG-21. ABERRANT SPLICING OF CLK1 IN PEDIATRIC HIGH-GRADE GLIOMAS DISRUPTS KEY ONCOGENIC TRANSCRIPTIONAL PROGRAMS

While the majority of somatic DNA coding alterations in pediatric brain tumors have been profiled, studies exploring transcriptional mechanisms remain underexplored. We systematically characterized aberrant splicing in primary tumors of seven broad histologies of pediatric brain tumors. We obtained...

Descripción completa

Detalles Bibliográficos
Autores principales: Naqvi, Ammar, Ennis, Brian, Corbett, Ryan, Lahiri, Aditya, Geng, Zhuangzhuang, Kin, Run, Gaonkar, Krutika, Rathi, Komal, Conkrite, Karina, Seghal, Priyanka, Hayer, Katharina, Kraya, Adam, Foster, Jessica, Madsen, Peter, Thomas-Tikhonenko, Andrei, Storm, Phillip, Resnick, Adam, Rokita, Jo Lynne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: High Grade Glioma/Gliomatosis Cerebri - HGG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260160/
http://dx.doi.org/10.1093/neuonc/noad073.170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260160/
http://dx.doi.org/10.1093/neuonc/noad073.170

Ejemplares similares