DIPG-35. IDENTIFYING DRIVER-SPECIFIC VULNERABILITIES IN PAEDIATRIC HIGH GRADE GLIOMA SUBTYPES

Paediatric high-grade gliomas (pHGGs) are incurable malignant brain tumours and a leading cause of cancer-related death in children. The majority of pHGGs carry lysine-to-methionine (K27M) or glycine-to-arginine/valine (G34R/V) mutations in histone variants H3.1 or H3.3. Moreover, histone mutations...

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Detalles Bibliográficos
Autores principales: De Cola, Antonella, McNicholas, Michael, Foss, Amelia, Lloyd, Cameron, Hébert, Steven, Faury, Damien, Andrade, Augusto Faria, Jabado, Nada, Kleinman, Claudia, Pathania, Manav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Diffuse Intrinsic Pontine Glioma/Diffuse Midline Gliomas - DPIG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260178/
http://dx.doi.org/10.1093/neuonc/noad073.082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260178/
http://dx.doi.org/10.1093/neuonc/noad073.082

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