IMMU-18. TARGETING GD2 IN THALAMIC DIFFUSE MIDLINE GLIOMA WITH TRANSIENT MRNA CAR T CELLS

Chimeric antigen receptor (CAR) T cells targeting the disialoganglioside GD2 have shown promise as a therapeutic for diffuse midline glioma (DMG). However, thalamic tumors have been excluded from clinical trials due to prior studies showing neurotoxicity and fatality when using virally transduced CA...

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Detalles Bibliográficos
Autores principales: Foster, Jessica, Madsen, Peter, Harvey, Kyra, Patterson, Luke, Griffin, Crystal, Stern, Allison, Storm, Phillip, Resnick, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Immunology/Immunotherapy - IMMU
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260187/
http://dx.doi.org/10.1093/neuonc/noad073.205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260187/
http://dx.doi.org/10.1093/neuonc/noad073.205

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