METB-06. HIGH FREQUENCY OF CLINICALLY RELEVANT ALTERATIONS DETECTED BY INTEGRATED TUMOR AND GERMLINE GENE PANEL TESTING IN CHILDREN WITH CNS TUMORS – RESULTS FROM THE TEXAS KIDSCANSEQ STUDY

BACKGROUND: Tumor and germline alterations detected by sequencing have the potential to inform management of children with CNS tumors. Comparative clinical utility data for available molecular sequencing modalities are needed to optimize testing strategies. METHODS: Cancer patients less than 18 year...

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Detalles Bibliográficos
Autores principales: Lin, Frank Y, Desrosiers, Lauren, Mangum, Ross, Reuther, Jacquelyn, Mohila, Carrie, Blessing, Melissa M, Aldave, Guillermo, Muzny, Donna M, Bernini, Juan Carlos, Gill, Jonathan, Griffin, Timothy, Tomlinson, Gail, Vallance, Kelly, Chintagumpala, Murali M, Scollon, Sarah, López-Terrada, Dolores H, Fisher, Kevin E, Roy, Angshumoy, Plon, Sharon E, Parsons, D Williams
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Genomics/Epigenomics/Metabolomics - METB
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260189/
http://dx.doi.org/10.1093/neuonc/noad073.123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260189/
http://dx.doi.org/10.1093/neuonc/noad073.123

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