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Modelling genetic stability in engineered cell populations

Predicting the evolution of engineered cell populations is a highly sought-after goal in biotechnology. While models of evolutionary dynamics are far from new, their application to synthetic systems is scarce where the vast combination of genetic parts and regulatory elements creates a unique challe...

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Detalles Bibliográficos
Autores principales: Ingram, Duncan, Stan, Guy-Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260955/
https://www.ncbi.nlm.nih.gov/pubmed/37308512
http://dx.doi.org/10.1038/s41467-023-38850-6