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Galectin-3 shapes toxic alpha-synuclein strains in Parkinson’s disease

Parkinson’s Disease (PD) is a neurodegenerative and progressive disorder characterised by intracytoplasmic inclusions called Lewy bodies (LB) and degeneration of dopaminergic neurons in the substantia nigra (SN). Aggregated α-synuclein (αSYN) is known to be the main component of the LB. It has also...

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Detalles Bibliográficos
Autores principales: García-Revilla, Juan, Boza-Serrano, Antonio, Jin, Yiyun, Vadukul, Devkee M., Soldán-Hidalgo, Jesús, Camprubí-Ferrer, Lluís, García-Cruzado, Marta, Martinsson, Isak, Klementieva, Oxana, Ruiz, Rocío, Aprile, Francesco A., Deierborg, Tomas, Venero, José Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261194/
https://www.ncbi.nlm.nih.gov/pubmed/37202527
http://dx.doi.org/10.1007/s00401-023-02585-x