Cargando…

Galectin-3 shapes toxic alpha-synuclein strains in Parkinson’s disease

Parkinson’s Disease (PD) is a neurodegenerative and progressive disorder characterised by intracytoplasmic inclusions called Lewy bodies (LB) and degeneration of dopaminergic neurons in the substantia nigra (SN). Aggregated α-synuclein (αSYN) is known to be the main component of the LB. It has also...

Descripción completa

Detalles Bibliográficos
Autores principales:	García-Revilla, Juan, Boza-Serrano, Antonio, Jin, Yiyun, Vadukul, Devkee M., Soldán-Hidalgo, Jesús, Camprubí-Ferrer, Lluís, García-Cruzado, Marta, Martinsson, Isak, Klementieva, Oxana, Ruiz, Rocío, Aprile, Francesco A., Deierborg, Tomas, Venero, José Luis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2023
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261194/ https://www.ncbi.nlm.nih.gov/pubmed/37202527 http://dx.doi.org/10.1007/s00401-023-02585-x

Ejemplares similares

Hyperinflammation and Fibrosis in Severe COVID-19 Patients: Galectin-3, a Target Molecule to Consider
por: Garcia-Revilla, Juan, et al.
Publicado: (2020)

The role of Galectin-3 in α-synuclein-induced microglial activation
por: Boza-Serrano, Antonio, et al.
Publicado: (2014)

Galectin-3, a rising star in modulating microglia activation under conditions of neurodegeneration
por: García-Revilla, Juan, et al.
Publicado: (2022)

A Facile Method to Produce N-Terminally Truncated α-Synuclein
por: Thrush, Rebecca J., et al.
Publicado: (2022)

APOE in the bullseye of neurodegenerative diseases: impact of the APOE genotype in Alzheimer’s disease pathology and brain diseases
por: Fernández-Calle, Rosalía, et al.
Publicado: (2022)

α-Synuclein Aggregation Is Triggered by Oligomeric Amyloid-β 42 via Heterogeneous Primary Nucleation
por: Vadukul, Devkee M., et al.
Publicado: (2023)

Galectin-3 is elevated in CSF and is associated with Aβ deposits and tau aggregates in brain tissue in Alzheimer’s disease
por: Boza-Serrano, Antonio, et al.
Publicado: (2022)

Targeting galectin-3 to counteract spike-phase uncoupling of fast-spiking interneurons to gamma oscillations in Alzheimer’s disease
por: Arroyo-García, Luis Enrique, et al.
Publicado: (2023)

The Diagnostic Potential of Amyloidogenic Proteins
por: Jin, Yiyun, et al.
Publicado: (2021)

Correlative optical photothermal infrared and X-ray fluorescence for chemical imaging of trace elements and relevant molecular structures directly in neurons
por: Gustavsson, Nadja, et al.
Publicado: (2021)

A mixture of Nordic berries improves cognitive function, metabolic function and alters the gut microbiota in C57Bl/6J male mice
por: Huang, Fang, et al.
Publicado: (2023)

Super‐Resolution Infrared Imaging of Polymorphic Amyloid Aggregates Directly in Neurons
por: Klementieva, Oxana, et al.
Publicado: (2020)

Alzheimer's Disease: Super‐Resolution Infrared Imaging of Polymorphic Amyloid Aggregates Directly in Neurons (Adv. Sci. 6/2020)
por: Klementieva, Oxana, et al.
Publicado: (2020)

Apolipoprotein E intersects with amyloid-β within neurons
por: Konings, Sabine C, et al.
Publicado: (2023)

Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer’s disease
por: Boza-Serrano, Antonio, et al.
Publicado: (2019)

Correction to: Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer’s disease
por: Boza-Serrano, Antonio, et al.
Publicado: (2023)

Galectin-3 causes enteric neuronal loss in mice after left sided permanent middle cerebral artery occlusion, a model of stroke
por: Cheng, Xiaowen, et al.
Publicado: (2016)

Amyloid Structural Changes Studied by Infrared Microspectroscopy in Bigenic Cellular Models of Alzheimer’s Disease
por: Paulus, Agnes, et al.
Publicado: (2021)

Nano-Infrared Imaging of Primary Neurons
por: Freitas, Raul O., et al.
Publicado: (2021)

Early-life stress elicits peripheral and brain immune activation differently in wild type and 5xFAD mice in a sex-specific manner
por: Bachiller, S., et al.
Publicado: (2022)

Alpha-Synuclein Expression in the Oligodendrocyte Lineage: an In Vitro and In Vivo Study Using Rodent and Human Models
por: Djelloul, Mehdi, et al.
Publicado: (2015)

The intracellular milieu of Parkinson’s disease patient brain cells modulates alpha-synuclein protein aggregation
por: Gustavsson, Nadja, et al.
Publicado: (2021)

Fluorescently Guided Optical Photothermal Infrared Microspectroscopy for Protein-Specific Bioimaging at Subcellular Level
por: Prater, Craig, et al.
Publicado: (2023)

Divergent Effects of Metformin on an Inflammatory Model of Parkinson’s Disease
por: Tayara, Khadija, et al.
Publicado: (2018)

Amyloidogenicity and toxicity of the reverse and scrambled variants of amyloid‐β 1‐42
por: Vadukul, Devkee M., et al.
Publicado: (2017)

Misfolded amyloid-β-42 impairs the endosomal–lysosomal pathway
por: Marshall, Karen E., et al.
Publicado: (2020)

Innate immune alterations are elicited in microglial cells before plaque deposition in the Alzheimer’s disease mouse model 5xFAD
por: Boza-Serrano, Antonio, et al.
Publicado: (2018)

Structure‐dependent effects of amyloid‐β on long‐term memory in Lymnaea stagnalis
por: Ford, Lenzie, et al.
Publicado: (2017)

Neuronal spreading and plaque induction of intracellular Aβ and its disruption of Aβ homeostasis
por: Roos, Tomas T., et al.
Publicado: (2021)

Microglia in Neurological Diseases: A Road Map to Brain-Disease Dependent-Inflammatory Response
por: Bachiller, Sara, et al.
Publicado: (2018)

Maternal separation differentially modulates early pathology by sex in 5xFAD Alzheimer’s disease-transgenic mice
por: Garcia, M.G., et al.
Publicado: (2023)

Galectin-3 Deletion Reduces LPS and Acute Colitis-Induced Pro-Inflammatory Microglial Activation in the Ventral Mesencephalon
por: Espinosa-Oliva, Ana M., et al.
Publicado: (2021)

Inflammatory Animal Models of Parkinson’s Disease
por: García-Revilla, Juan, et al.
Publicado: (2022)

Unveiling the Rational Development of Stimuli-Responsive Silk Fibroin-Based Ionogel Formulations
por: Shmool, Talia A., et al.
Publicado: (2023)

The human bone marrow harbors a CD45(−) CD11B(+) cell progenitor permitting rapid microglia‐like cell derivative approaches
por: Bruzelius, Andreas, et al.
Publicado: (2020)

FRET-Based Screening Identifies p38 MAPK and PKC Inhibition as Targets for Prevention of Seeded α-Synuclein Aggregation
por: Svanbergsson, Alexander, et al.
Publicado: (2021)

Who let the dogs out?: detrimental role of Galectin-3 in hypoperfusion-induced retinal degeneration
por: Manouchehrian, Oscar, et al.
Publicado: (2015)

Inflamed In Vitro Retina: Cytotoxic Neuroinflammation and Galectin-3 Expression
por: Bauer, Patrik Maximilian, et al.
Publicado: (2016)

Forced treadmill exercise can induce stress and increase neuronal damage in a mouse model of global cerebral ischemia
por: Svensson, Martina, et al.
Publicado: (2016)

Aβ/Amyloid Precursor Protein-Induced Hyperexcitability and Dysregulation of Homeostatic Synaptic Plasticity in Neuron Models of Alzheimer’s Disease
por: Martinsson, Isak, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_5hh08282q8s52flfmp557708o5