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Increased mRNA expression of CDKN2A is a transcriptomic marker of clinically aggressive meningiomas

Homozygous deletion of CDKN2A/B was recently incorporated into the World Health Organization classification for grade 3 meningiomas. While this marker is overall rare in meningiomas, its relationship to other CDKN2A alterations on a transcriptomic, epigenomic, and copy number level has not yet been...

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Detalles Bibliográficos
Autores principales: Wang, Justin Z., Patil, Vikas, Liu, Jeff, Dogan, Helin, Tabatabai, Ghazaleh, Yefet, Leeor S., Behling, Felix, Hoffman, Elgin, Bunda, Severa, Yakubov, Rebecca, Kaloti, Ramneet, Brandner, Sebastian, Gao, Andrew, Cohen-Gadol, Aaron, Barnholtz-Sloan, Jill, Skardelly, Marco, Tatagiba, Marcos, Raleigh, David R., Sahm, Felix, Boutros, Paul C., Aldape, Kenneth, Nassiri, Farshad, Zadeh, Gelareh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261216/
https://www.ncbi.nlm.nih.gov/pubmed/37093270
http://dx.doi.org/10.1007/s00401-023-02571-3