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Estimating prognostic relevant cutoff values for a multiplex PCR detecting BCR::ABL1 in chronic myeloid leukemia patients on tyrosine kinase inhibitor therapy in resource-limited settings

The prognosis of chronic myeloid leukemia (CML) on tyrosine kinase inhibitor (TKI) treatment is based on the quantification of BCR::ABL1 fusion gene transcript copy number, harmonized by an international scale (IS) based on TaqMan-based real-time quantitative PCR (qRT-PCR). In Ethiopia, as in most l...

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Detalles Bibliográficos
Autores principales: Hailu, Saifu, Kinde, Samuel, Cross, Michael, Tsegaye, Aster, Kelemu, Tsehayneh, Seifu, Daniel, Alemayehu, Dawit, Tarekegn, Azeb, Jabessa, Gutema, Abeje, Desalegn, Abebe, Markos, Sherif, Abdulaziz, Tadesse, Fisihatsion, Platzbecker, Uwe, Howe, Rawleigh, Gebremedhin, Amha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261237/
https://www.ncbi.nlm.nih.gov/pubmed/37212909
http://dx.doi.org/10.1007/s00277-023-05254-x