Tumor-associated macrophages promote cisplatin resistance in ovarian cancer cells by enhancing WTAP-mediated N6-methyladenosine RNA methylation via the CXCL16/CXCR6 axis

PURPOSE: Tumor-promotive tumor-associated macrophages (TAMs) and the CXCL16/CXCR6 axis have been reported to be correlated with the limited efficacy of chemotherapy in ovarian cancer (OC). However, the role of TAM-secreted CXCL16 and the mechanism by which it affects the cisplatin (DDP) resistance o...

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Detalles Bibliográficos
Autores principales: Hong, Lan, Wang, Xiuzhen, Zheng, Lang, Wang, Shengtan, Zhu, Genhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261262/
https://www.ncbi.nlm.nih.gov/pubmed/37272931
http://dx.doi.org/10.1007/s00280-023-04533-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261262/
https://www.ncbi.nlm.nih.gov/pubmed/37272931
http://dx.doi.org/10.1007/s00280-023-04533-8

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