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The radioprotectant nano-genistein enhances radiotherapy efficacy of lung tumors in mice

BACKGROUND: Radiotherapy for non-small cell lung cancer (NSCLC) can be dose-limiting due to treatment-related toxicities. Genistein has been shown to be a robust radioprotective agent in preclinical models. A novel genistein oral nanosuspension formulation (nano-genistein) has demonstrated efficacy...

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Detalles Bibliográficos
Autores principales: Kaytor, Michael D., Serebrenik, Artur A., Lapanowski, Karen, McFall, Debra, Jones, Matthew, Movsas, Benjamin, Simone, Charles B., Brown, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261856/
https://www.ncbi.nlm.nih.gov/pubmed/37323169
http://dx.doi.org/10.21037/tlcr-22-856