BRCA mutations detected by tumour next-generation sequencing in non-small cell lung cancer: impact on response to therapy and disease course

BACKGROUND: Data regarding the prevalence and clinical relevance of BRCA mutations in non-small cell lung cancer (NSCLC) is limited. Our objective was to evaluate the impact of pathogenic BRCA variants detected by tumour next-generation sequencing (NGS) on disease course and response to therapy. MET...

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Detalles Bibliográficos
Autores principales: Tschernichovsky, Roi, Averbuch, Itamar, Goldstein, Daniel Alex, Mutai, Raz, Dudnik, Elizabeth, Rotem, Ofer, Laufer-Geva, Smadar, Peled, Nir, Goldberg, Yael, Zer, Alona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261861/
https://www.ncbi.nlm.nih.gov/pubmed/37323181
http://dx.doi.org/10.21037/tlcr-22-594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261861/
https://www.ncbi.nlm.nih.gov/pubmed/37323181
http://dx.doi.org/10.21037/tlcr-22-594

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