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BRCA mutations detected by tumour next-generation sequencing in non-small cell lung cancer: impact on response to therapy and disease course
BACKGROUND: Data regarding the prevalence and clinical relevance of BRCA mutations in non-small cell lung cancer (NSCLC) is limited. Our objective was to evaluate the impact of pathogenic BRCA variants detected by tumour next-generation sequencing (NGS) on disease course and response to therapy. MET...
Autores principales: | Tschernichovsky, Roi, Averbuch, Itamar, Goldstein, Daniel Alex, Mutai, Raz, Dudnik, Elizabeth, Rotem, Ofer, Laufer-Geva, Smadar, Peled, Nir, Goldberg, Yael, Zer, Alona |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261861/ https://www.ncbi.nlm.nih.gov/pubmed/37323181 http://dx.doi.org/10.21037/tlcr-22-594 |
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