Cancer's Dark Matter: Lighting the Abyss Unveils Universe of New Therapies

The authors of a recent study identified noncanonical peptides (NCP) presented by cancer cells’ HLA and observed lack of reactivity to these antigens by endogenous tumor-reactive T cells. In vitro sensitization generated NCP-reactive T cells that recognized epitopes shared by a majority of cancers t...

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Detalles Bibliográficos
Autores principales: Fox, Bernard A., Urba, Walter J., Jensen, Shawn M., Page, David B., Curti, Brendan D., Sanborn, Rachel E., Leidner, Rom S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
CCR Translations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261915/
https://www.ncbi.nlm.nih.gov/pubmed/37040070
http://dx.doi.org/10.1158/1078-0432.CCR-23-0422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261915/
https://www.ncbi.nlm.nih.gov/pubmed/37040070
http://dx.doi.org/10.1158/1078-0432.CCR-23-0422

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