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Dynamics of Sequence and Structural Cell-Free DNA Landscapes in Small-Cell Lung Cancer

PURPOSE: Patients with small-cell lung cancer (SCLC) have an exceptionally poor prognosis, calling for improved real-time noninvasive biomarkers of therapeutic response. EXPERIMENTAL DESIGN: We performed targeted error-correction sequencing on 171 serial plasmas and matched white blood cell (WBC) DN...

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Detalles Bibliográficos
Autores principales: Sivapalan, Lavanya, Iams, Wade T., Belcaid, Zineb, Scott, Susan C., Niknafs, Noushin, Balan, Archana, White, James R., Kopparapu, Prasad, Cann, Christopher, Landon, Blair V., Pereira, Gavin, Velculescu, Victor E., Hann, Christine L., Lovly, Christine M., Anagnostou, Valsamo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261918/
https://www.ncbi.nlm.nih.gov/pubmed/37071497
http://dx.doi.org/10.1158/1078-0432.CCR-22-2242